Changes in the oxidative status and serum trace element levels in dogs with mammary tumours

The purpose of the study was to evaluate the changes in oxidative status and serum trace element levels by determining the concentrations of malondialdehide (MDA), nitric oxide (NO), ascorbic acid, and certain trace elements. The study included 15 clinically healthy female dogs and 15 dogs with malignant mammary tumour. In conclusion, the results of present study provide evidence of enhanced oxidative stress in dogs with mammary tumours, and can be suggested that Fe and Cu play a role in the generation of ROS and the enhancement of lipid peroxidation in dogs with mammary tumours.