Comparative evaluation of conventional and dynamic magnetic resonance imaging of the pituitary microadenomas

Objective: This study tried to determine if there is a difference between standard and dynamic MR examination in detection of pituitary microadenoma. Subjects and methods: We have included twenty seven patients with suspicious pituitary tumor. All patients have been hospitalized for endocrinologyc examination between June 2007 and May 2008 in Institute for Endocrinology, diabetes and metabolic diseases of Clinical Center of Serbia. MR examinations have been preformed in MR Center of Clinical Center of Serbia. Results: Twenty seven patients were included in our study. Only in four of them pituitary microadenoma was detected using dynamic MR examination. One was somatotrophin secreting adenoma, and three were corticotrophin realizing adenomas. There were no statistically significant differences between conventional and dynamic MR examination. Conclusion: Dynamic MR Examination as method can hardly match standard MR examination which remains standard in detection of pituitary microadenomas. CILJ RADA: Ovom studijom smo pokusali da utvrdimo da li postoji statisticki znacajna razlika izmedju standardnog i dinamskog MR pregleda u detekciji mikroadenoma hipofizne zlezde. METODE I MATERIJALI: U studiju je ukljuceno 27 pacijenata sa suspektnim tumorom hipofize. Svi pacijenti su hospitalizovani radi endokrinoloskog ispitivanja u periodu od juna 2007 do maja 2008. godine u Institutu za endokrinologiju, dijabetes i bolesti metabolizma Klinickog centra Srbije. MR pregledi selarne regije uradjeni su u Centru za MR Klinickog centra Srbije. REZULTATI: Od 27 pacijenata kod 4 je detektovan mikroadenom dinamskim MR pregledom, od kojih jedan somatotropni, a preostala tri su kortikotropni adenomi. Nije ustanovljena statisticki znacajna razlika u broju pozitivnih nalaza izmedju klasicnog MR i dinamskog MR pregleda. ZAKLJUCAK: Dinamski MR pregled hipofize nema prednost nad klasicnim MR pregledom koji i dalje predstavlja zlatni standard u detekciji mikroadenoma.