PHYTOCHEMICAL PURIFICATION OF ACTIVE CONSTITUENTS ISOLATED FROM ROOT OF THE MEDICINAL HERB, CARALLUMA QUADRANGULA

Objective: Present study aim for the purification of quantitative phytochemical compounds from roots of Caralluma quadrangula belongs to the family Asclepiadaceae. This type of plants can be use as folk medicine to take care of wide diversity of health and diseases situation. Methods: Preliminary phytochemical analysis for different type of chemical compounds by using various chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry. Results: The quantitative phytochemical analysis of this species exhibited the presence four pure compounds, hydroxyoplopan-4-one (4.5 mg), dihydroxyeudesm-4(15)-ene (5.0 mg), and quercetin- rhamnopyranosyl-D-glucopyranose (Rutin) (7.0 mg). Conclusion: From this study, it can be concluded that the species found four pure compounds from C. quadrangula. Peer Review History: Received 25 July 2020; Revised 10 August; Accepted 28 August, Available online 15 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Name: Marwa A. A. Fayed Affiliation: Faculty of Pharmacy, University of Sadat City, Egypt E-mail: maafayed@gmail.com Name: Dr. Ali Gamal Ahmed Al-kaf Affiliation: Sana'a university, Yemen E-mail: alialkaf21@gmail.com Name: Ahmad Najib Affiliation: Department of Pharmacognosy-Phytochemystry Universitas Muslim Indonesia-Indonesia E-mail: ahmad.najib@umi.ac.id Co