UV Spectrophotometric Method for Estimation of Voriconazole in Bulk Form

This study presents a validated UV spectrophotometric method for the precise estimation of voriconazole in bulk formulations. Voriconazole, an essential antifungal agent, demands accurate quantification for its pharmaceutical applications. The proposed method leverages the sensitivity of UV spectroscopy to determine voriconazole concentrations effectively. The method's validation adheres to regulatory guidelines, ensuring reliability and accuracy. Spectrophotometric analysis was performed within a specific wavelength range, demonstrating linearity, precision, accuracy, and robustness across different concentrations of voriconazole. Parameters such as specificity, sensitivity, and stability were evaluated to affirm the method's suitability for routine analysis. The results indicate the method's efficacy in quantifying voriconazole in bulk and semi-solid forms with high precision and sensitivity. This validated UV spectrophotometric method presents a valuable tool for pharmaceutical analysis, facilitating quality control and assurance in voriconazole formulations. Keywords: Voriconazole, UV spectrophotometry, Anti-fungal, semi-solid formulation, Beer’s Lambert’s law.