BANANA PEEL FLAKES ALLEVIATE BLOOD GLUCOSE AND STRESS IN A DOSE-DEPENDENT MANNER

Objective: This study aimed to evaluate the antidiabetic and antidepressant effects of banana peel flakes in streptozotocin-induced diabetic rats. Methods: Twenty-five male Wistar rats were classified into five groups with different treatments. Groups I to IV were diabetic rats model groups that con...

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Veröffentlicht in:International journal of pharmacy and pharmaceutical sciences 2020-06, p.75-81
Hauptverfasser: MELIALA, ANDREANYTA, SUMIWI, YUSTINA ANDWI ARI, NARWIDINA, PARAMITA, RINI, SRI LESTARI SULISTYO, SETYANINGSIH, WIDIASTUTI
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Sprache:eng
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Zusammenfassung:Objective: This study aimed to evaluate the antidiabetic and antidepressant effects of banana peel flakes in streptozotocin-induced diabetic rats. Methods: Twenty-five male Wistar rats were classified into five groups with different treatments. Groups I to IV were diabetic rats model groups that consumed only standard diet, standard diet containing 5%, 10%, and 20% of banana peel flakes, respectively. While group V was a healthy control group fed a standard diet. Immunohistochemistry staining was measured to examine serotonin expression in the colon and pancreas. Results: The diabetic rats treated with 20% banana peel flakes had a lower blood glucose concentration (p
ISSN:2656-0097
0975-1491
DOI:10.22159/ijpps.2020v12i8.37659