ESSENTIAL OILS AND METHYLGLYOXAL: A POSSIBLE ALTERNATIVE TREATMENT FOR ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS

Objective: Essential oils are of significant interest in today’s world of healthcare because these compounds have a variety of medicinal properties. In this study, we evaluated the in vitro antibiotic role of essential oils as a possible alternative treatment in combatting Methicillin-resistant Stap...

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Veröffentlicht in:International journal of pharmacy and pharmaceutical sciences 2016-09, Vol.8 (9), p.107
Hauptverfasser: Cieslak, Erin, Mack, James P., Rojtman, Albert
Format: Artikel
Sprache:eng
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Zusammenfassung:Objective: Essential oils are of significant interest in today’s world of healthcare because these compounds have a variety of medicinal properties. In this study, we evaluated the in vitro antibiotic role of essential oils as a possible alternative treatment in combatting Methicillin-resistant Staphylococcus aureus (MRSA).Methods: In conjunction with carrier oils, three essential oils (cassia, cinnamon bark, and thyme), as well as methylglyoxal were tested on MRSA using the Kirby-Bauer disc diffusion method.Results: The minimum inhibitory concentration of each tested essential oil and methylglyoxal in carrier oil was determined to be 25% essential oil and 75% carrier oil mixture. This concentration worked much more effectively than the standard antibiotic, vancomycin, which is currently used to treat MRSA infections.Conclusion: Antibacterial emollients made from naturally occurring products like essential oils can be cost-effective alternatives to antibiotics. The results of this research show that these emollients are more effective against MRSA than standard antibiotics in cell culture.
ISSN:0975-1491
0975-1491
DOI:10.22159/ijpps.2016.v8i9.12242