ADHERENCE AND ASSOCIATED ADVERSE DRUG REACTION WITH ANTIDEPRESSANTS MEDICATION AMONG DEPRESSION PATIENTS IN PSYCHIATRIC HOSPITAL IN POKHARA, NEPAL

Background: The present study determined the prescription pattern of antidepressants, adverse drug reactions (ADRs), the level of adherence, and factors affecting it. Methods: This prospective cross-sectional study was conducted with depression patients (n=174; 55.74% female) from August 2019 to November 2019 at a psychiatric hospital of Pokhara, Kaski, Nepal. The Naranjo ADR Probability Scale was employed to assess the ADRs. The rate of medication adherence (MA) was determined using Morisky MA Measurement Scale-Eight. Descriptive statistics (median, interquartile range, frequency, and percentage), bivariate analysis, and Chi-square test were used; p