STUDY OF POTENTIAL ANTITUSSIVE ACTIVITY OF GLYCYRRHIZA GLABRA GRANULES BY USING A COUGH MODEL INDUCED BY SULPHUR DIOXIDE GAS IN MICE

In respiratory diseases cough is most common symptom. When cough becomes severe, opioids are potent, but they have side effects like sedation, constipation. Therefore, there is a necessary to have effective antitussive formulation, which does not have respiratory depressant activity. The present study was carried out to analysis antitussive activity of Glycyrrhiza glabra L. using a cough model induced by sulphur dioxide gas in experimental mice. The effect of the granules of Glycyrrhiza glabra extract on SO2 gas induced cough in experimental animals have very significant effects at the level of p