EXTENDED MANTLE RADIOTHERAPY IN HODGKIN'S DISEASE AND MALIGNANT LYMPHOMA

The extended mantle field eliminates the necessity for splicing at the level of the diaphragm and thereby eliminates the potential for radiation-induced transverse myelitis. Our experience to date with 95 patients with H.D. or M.L. is described. Modifications in technique, including changes in the g...

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Veröffentlicht in:	Amer. J. Roentgenol., Radium Ther. Nucl. Med., v. 121, no. 4, pp. 772-788 Radium Ther. Nucl. Med., v. 121, no. 4, pp. 772-788, 1974-08, Vol.121 (4), p.772-788
Hauptverfasser:	MARKS, J. E, MORAN, E. M, GRIEM, M. L, ULTMANN, J. E
Format:	Artikel
Sprache:	eng
Schlagworte:	ABDOMEN Blood Cell Count DOSE-RESPONSE RELATIONSHIPS Esophagitis - etiology EXTERNAL IRRADIATION Follow-Up Studies FRACTIONATED IRRADIATION GEOMETRY Hodgkin Disease - drug therapy Hodgkin Disease - mortality Hodgkin Disease - pathology Hodgkin Disease - radiotherapy HODGKINS DISEASE- RADIOTHERAPY Humans LYMPH NODES Lymphoma - pathology Lymphoma - radiotherapy Lymphoma, Large B-Cell, Diffuse - pathology Lymphoma, Large B-Cell, Diffuse - radiotherapy Lymphoma, Non-Hodgkin - pathology Lymphoma, Non-Hodgkin - radiotherapy LYMPHOMAS- RADIOTHERAPY MEDIASTINUM MYELITIS N48510 -Life Sciences-Radiation Effects on Animals-Man NECK Neoplasm Recurrence, Local Pericarditis, Constrictive - etiology PHOTON BEAMS Pneumonia - etiology RADIATION DOSES Radiation Protection - instrumentation RADIOINDUCTION Radiotherapy - adverse effects Radiotherapy - methods Radiotherapy Dosage RADIOTHERAPY- RADIATION DOSE DISTRIBUTIONS Recurrence Retrospective Studies SHIELDS SIDE EFFECTS Tracheoesophageal Fistula - etiology
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Zusammenfassung:	The extended mantle field eliminates the necessity for splicing at the level of the diaphragm and thereby eliminates the potential for radiation-induced transverse myelitis. Our experience to date with 95 patients with H.D. or M.L. is described. Modifications in technique, including changes in the geometry of the field, shielding, time, dose, fractionation, and simulation are described. End results, an analysis of failures, and complications encountered are presented. Morbidity was acceptable despite the increase in integral dose, particularly in young patients who were not debilitated by disease. The danger of radiation-induced esophagitis, dehydration, hemoconcentration, and pulmonary embolism is stressed.
ISSN:	0361-803X 0002-9580 1546-3141
DOI:	10.2214/ajr.121.4.772