Protein Experimental Information Management System (PREIMS) Based on Ontology: Development and Applications

We developed a new information management system, Protein Experimental Information Management System (PREIMS), which has the ontology-based functions for quality control, validation, scalability, and information sharing. Its contents are mainly experimental protocols for the analyses of protein structures and functions, and their results. They are stored separately in the PREIMS database (DB), as the ontology based protocol data and the result data. The synchrotron experimental information was stored as the latter result data in Extensible Markup Language (XML). Furthermore we converted those protocols in the format of Resource Description Framework (RDF) for integration with other biological information resources.