Spontaneous and Mitomycin-C Induced Sister Chromatid Exchanges in Cells from Patients with Tuberous Sclerosis

Spontaneous and Mitomycin-C Induced Sister Chromatid Exchanges in Cells from Patients with Tuberous Sclerosis

Lymphocytes from four normal controls and from four patients with TS are studied for SCEs and the cell cycle kinetics in the MMC-treated cultures. The results reveal that TS lymphocytes have almost the same proliferative kinetics and SCE frequencies as normal cells both in untreated cultures and whe...

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Veröffentlicht in:Proceedings of the Japan Academy, Series B Series B, 1985, Vol.61(1), pp.32-34
Hauptverfasser: IIJIMA, Sumio, HIGURASHI, Makoto, TAKESHITA, Tatsuya, FUNAHASHI, Masuko
Format: Artikel
Sprache:eng
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Zusammenfassung:Lymphocytes from four normal controls and from four patients with TS are studied for SCEs and the cell cycle kinetics in the MMC-treated cultures. The results reveal that TS lymphocytes have almost the same proliferative kinetics and SCE frequencies as normal cells both in untreated cultures and when exposed to MMC.
ISSN:0386-2208
1349-2896
DOI:10.2183/pjab.61.32