Immunological studies on children with growth hormone deficiency -Effects of growth hormone replacement therapy

Immunological studies on children with growth hormone deficiency -Effects of growth hormone replacement therapy

Several kinds of killer cell activities including natural killer (NK) and lymphokine activated killer (LAK) activities, and subpopulations of lymphocytes were studied in 12 children with growth hormone (GH) deficiency before and during treatment with the intramuscular administration of 0.5U per Kg m...

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Veröffentlicht in:Japanese Journal of Clinical Immunology 1989/12/31, Vol.12(6), pp.615-622
Hauptverfasser: Fujieda, Mikiya, Wakiguchi, Hiroshi, Araki, Kumiko, Kurashige, Takanobu
Format: Artikel
Sprache:eng
Schlagworte:
growth hormon (GH) deficiency
killer activity
lymphocyte subset
replacement therapy
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Zusammenfassung:Several kinds of killer cell activities including natural killer (NK) and lymphokine activated killer (LAK) activities, and subpopulations of lymphocytes were studied in 12 children with growth hormone (GH) deficiency before and during treatment with the intramuscular administration of 0.5U per Kg methionyl growth hormone weekly. The results as follows: (1) The mean of natural killer (NK) activity against K 562 cells in 12 patients before GH therapy was significantly (p
ISSN:0911-4300
1349-7413
DOI:10.2177/jsci.12.615