Carbamazepine-Induced Systemic Lupus Erythematosus-Like Disease

Carbamazepine-Induced Systemic Lupus Erythematosus-Like Disease

A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ ; Tegretol®) used against benign Rolandic epilepsy. Clinical symptoms and leukopenia normalized after...

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Veröffentlicht in:Internal Medicine 1992, Vol.31(11), pp.1303-1305
Hauptverfasser: KANNO, Takashi, MIYATA, Masayuki, KAZUTA, Yoshihiro, SATO, Yukio, NISHIMAKI, Tomoe, KASUKAWA, Reiji
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
anticonvulsant
Carbamazepine - adverse effects
drug-induced SLE
Epilepsy - drug therapy
Female
Humans
Lupus Erythematosus, Systemic - chemically induced
Lupus Erythematosus, Systemic - diagnosis
Lupus Erythematosus, Systemic - drug therapy
Prednisolone - therapeutic use
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Zusammenfassung:A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ ; Tegretol®) used against benign Rolandic epilepsy. Clinical symptoms and leukopenia normalized after discontinuation of CBZ and administration of prednisolone at 40mg. The cases of CBZ-induced SLE reported in the literature were reviewed. (Internal Medicine 31 : 1303-1305, 1992)
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.31.1303