Role of antibiotic prophylaxis in clean and clean contaminated elective surgery

Antibiotic prophylaxis is a recognized concept in surgery. We studied the need for prophylaxis in clean and clean contaminated surgery in the setting of third world tertiary care center. A randomized single blind study was conducted with three arms. 278 patients of ASA and 2 were included in this study. They were randomized to prophylaxis with Cefuroxime, triple regime and placebo. The placebo wing was terminated prematurely due to unacceptable infection rate and Cefuroxime was found to be equal or better than triple regime in our study.