Risk predictive role of hypernatremia for occurrence of sepsis-induced acute kidney injury

Septic acute kidney injury (AKI), identified when sepsis and AKI present concurrently, is a syndrome of acute function impairment and organ damage, which accounts for ~50% AKI in the intensive care unit (ICU). This study retrospectively reviewed 591 patients who were diagnosed with sepsis and admitted to the ICU of Beijing Friendship Hospital from January 2009 to December 2014. According to the concentration of serum sodium, the 591 patients were further divided into 3 groups: normal group, hyponatremia group, and hypernatremia group. The arterial partial pressure of carbon dioxide (PaCO2, P=0.014), concentration of sodium (Na+, P