Bacopa monnieri L “Brahmi”: An Ayurvedic Herb with Promising Antibacterial Properties and its Future Application in Oral Hygiene

The investigation explores the characteristics of Bacopa monnieri, a renowned herb in Ayurvedic medicine referred to as 'Brahmi' for its wide-ranging applications in pharmacology, cosmetics, nutraceuticals, etc., showcasing efficacy against ulcers, inflammation, and asthma. The present study explores the antibacterial potential of B. monnieri for oral hygiene, particularly its impact on dental caries causing microorganisms, demonstrating favorable outcomes in both traditional and modern medical practices, offering cognitive enhancement and overall health benefits. The research aims to assess the antibacterial effectiveness against oral bacteria (Streptococcus mutans, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa) utilizing the agar cup/plate technique by testing six different concentrations of methanolic extract derived from Bacopa monnieri (L.) Pennell. The results indicate that Bacopa monnieri Methanolic extract (BmMe) exhibits significant antimicrobial activity against both Gram-positive and Gram-negative bacterial strains, with a concentration-dependent response observed in the zone of inhibition (ZOI) diameters, sup-ported by the presence of various bioactive compounds identified through phytochemical screening, suggesting its potential as a natural antimicrobial agent and encouraging further exploration for incorporating it into mouthwash formulations as an innovative oral hygiene practices.