Long non-coding RNA MINCR regulates the growth and metastasis of human osteosarcoma cells via Wnt/β-catenin signaling pathway

There is concrete evidence that lncRNA-MINCR is involved in tumorigenesis of a number of human cancers through modulation of Wnt/β-catenin signaling pathway. However, the characterization of regulatory role of lncRNA-MINCR has not been worked out in osteosarcoma yet. The present study was undertaken...

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Veröffentlicht in:Acta biochimica polonica 2022-06
Hauptverfasser: Bai, Sunpeng, Li, Yongjiang, Wang, Yuancheng, Zhou, Gaoli, Liu, Cheng, Xiong, Wen, Chen, Junfeng
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Sprache:eng
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Zusammenfassung:There is concrete evidence that lncRNA-MINCR is involved in tumorigenesis of a number of human cancers through modulation of Wnt/β-catenin signaling pathway. However, the characterization of regulatory role of lncRNA-MINCR has not been worked out in osteosarcoma yet. The present study was undertaken to explore the role of lncRNA-MINCR in human osteosarcoma. The osteosarcoma tissues and cell lines were found to exhibit significant (P
ISSN:0001-527X
1734-154X
DOI:10.18388/abp.2020_5804