Preparation and thermoresponsive behaviors of UV-crosslinked gelatin nanogels

Preparation and thermoresponsive behaviors of UV-crosslinked gelatin nanogels

UV-crosslinked gelatin nanogel was prepared without using chemical crosslinking agents and its thermoresponsive behaviors were investigated. The particle size of the nanogels decreased on heating, which is attributed to the helix-to-coil transition of gelatin. On the other hand, the increase in the...

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Veröffentlicht in:Journal of Biorheology 2018, Vol.32(1), pp.15-19
Hauptverfasser: Maki, Yasuyuki, Saito, Wataru, Dobashi, Toshiaki
Format: Artikel
Sprache:eng
Schlagworte:
drug delivery
gelatin
nanoparticle
thermoresponsive behavior
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Zusammenfassung:UV-crosslinked gelatin nanogel was prepared without using chemical crosslinking agents and its thermoresponsive behaviors were investigated. The particle size of the nanogels decreased on heating, which is attributed to the helix-to-coil transition of gelatin. On the other hand, the increase in the particle size on cooling was not observed in the quiescent solutions, but was noticeably accelerated by the application of shear stress.
ISSN:1867-0466
1867-0474
DOI:10.17106/jbr.32.15