On the Intestinal Secretion in Dogs in the Interdigestive Period

From a Thiry fistula provided in dogs, enteric juice was collected either without inserting any Ga-ther or using catheters of gummi or glass of various size and length. When no catheter was inserted or catheter of smaller size or length, compared with those of fistula, periodical output of the juice was observ-able though rnot, always, but rather frequently. And the periodicity was more regular in compari-son to previous experi-mentalists, while it was not so regular, or other-wise expressed, not so strictly periodical as the description of Boldyreff. The active period was usually noted as ten minutes and the quiescent period as one hour as a mean, or from a half hour to one and a half hours, and the figures are about the half of those of Boldyreff. The figures given in the reviews of that author, one in 1911 and the other in 1929, are somewhat different from each other. When catheters of large size and length were used, the output of juice inclined to lose its periodicity, that is there were fluctuations in the output rate, but it was irregular and of insignificant magnitude, so that finally it has no periodical character at all. The results show clearly that the so-called “periodical secretion, ” or strictly spoken, “ periodical output” of enteric iice, observed by means of Thiry, Thiry-Vella fistula or something like pz kcdures, can be abolish-ed by restricting influence of intestinal movements: that is, , the latter act to push out periodically the juice, which is secreted highly probably continuously. And further, the writer had opportunities to observe the output of juice in a rhythm of about twenty times a minute, which corres-ponds to that of intestinal movements. The periodicity, spoken by Boldyreff, especially in his first review in 1911, for example, also of the output of intestinal juice, is also of highly strictness. Such an exact periodicity is never found in the communi-cations of other authors. How that author would come to see such a data has been suggested with right in a previous paper of Ooisi rê the pancreatic secretion. Briefly concluded: The “periodical” ouptut of intestinal juice in the interdigestive period in dogs, which is rather frequently ob-servable, and has a periodicity of the active period of ten minutes and the quiescent period of one hour, roughly speaking, is due to the intestinal movements and not to having of its secretion the periodicity. There is no evidence of existance of periodicity in the secretion of enteric jui