Fatal Acute Interstitial Pneumonia Induced by Low-Dose Doxorubicin and Vindesine

ISAWA, T., ONO, R., MOTOMIYA, M. and TAMAHASHI, N. Fatal Acute Interstitial Pneumonia Induced by Low-Dose Doxorubicin and Vindesine. Tohoku J. Exp. Med., 1989, 158 (2), 149-154-A 53-year-old female smoker with small cell carcinoma of the lung with cerebral metastases was initially treated with whole...

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Veröffentlicht in:	The Tohoku Journal of Experimental Medicine 1989, Vol.158(2), pp.149-154
Hauptverfasser:	ISAWA, TOYOHARU, ONO, REIKO, MOTOMIYA, MASAKICHI, TAMAHASHI, NOBUAKI
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Brain Neoplasms - drug therapy Brain Neoplasms - radiotherapy Brain Neoplasms - secondary bronchogenic carcinoma cancer chemotherapy Carcinoma, Small Cell - complications Carcinoma, Small Cell - drug therapy Carcinoma, Small Cell - radiotherapy doxorubicin Doxorubicin - administration & dosage Doxorubicin - adverse effects drug-induced interstitial pneumonia Female Histocytochemistry Humans Lung Neoplasms - complications Lung Neoplasms - drug therapy Lung Neoplasms - radiotherapy Middle Aged Pulmonary Fibrosis - chemically induced vindensine Vindesine - administration & dosage Vindesine - adverse effects
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Zusammenfassung:	ISAWA, T., ONO, R., MOTOMIYA, M. and TAMAHASHI, N. Fatal Acute Interstitial Pneumonia Induced by Low-Dose Doxorubicin and Vindesine. Tohoku J. Exp. Med., 1989, 158 (2), 149-154-A 53-year-old female smoker with small cell carcinoma of the lung with cerebral metastases was initially treated with whole brain radiation with favorable responses. She developed fulminant and fatal interstitial pneumonia following administration of 30mg of doxorubicin and 6mg of vindesine. Histopathology revealed that the interstitial pneumonia was compatible with a druginduced penumonia.
ISSN:	0040-8727 1349-3329
DOI:	10.1620/tjem.158.149