The Effect of Protamine on Proteinuria and Glomerular Sclerosis in Aminonucleoside Nephropathy

SAITO, T., YAMAKAGE, K., KUROSAWA, K., KYOGOKU, Y., FURUYAMA, T. and YOSHINAGA, K. The Effect of Protamine on Proteinuria and Glomerular Sclerosis in Aminonucleoside Nephropathy. Tohoku J. exp. Med., 1982, 136 (4), 461-462-An administration of protamine sulfate combined with aminonucleoside of purom...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Tohoku Journal of Experimental Medicine 1982, Vol.136(4), pp.461-462
Hauptverfasser:	SAITO, TAKAO, YAMAKAGE, KEI, KUROSAWA, KOSEI, KYOGOKU, YOSHIO, FURUYAMA, TAKASHI, YOSHINAGA, KAORU
Format:	Artikel
Sprache:	eng
Schlagworte:	aminonucleoside nephropathy Animals focal glomerular sclerosis Kidney Glomerulus - drug effects Kidney Glomerulus - pathology Male nephrotic syndrome Nephrotic Syndrome - chemically induced Nephrotic Syndrome - pathology protamine Protamines - pharmacology Proteinuria Puromycin - analogs & derivatives Puromycin Aminonucleoside - toxicity Rats Rats, Inbred Strains Sclerosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	SAITO, T., YAMAKAGE, K., KUROSAWA, K., KYOGOKU, Y., FURUYAMA, T. and YOSHINAGA, K. The Effect of Protamine on Proteinuria and Glomerular Sclerosis in Aminonucleoside Nephropathy. Tohoku J. exp. Med., 1982, 136 (4), 461-462-An administration of protamine sulfate combined with aminonucleoside of puromycin (AN) could produce in rats severe nephrotic syndrome and histological changes similar to focal glomerular sclerosis more distinctly than AN alone. This may be attributed to the action of protamine which seemed to enhance the effect of AN, causing polyanion loss at the glomerular basement membrane.
ISSN:	0040-8727 1349-3329
DOI:	10.1620/tjem.136.461