Effect of Ingestion of Food on Adrenal 17-Hydroxycorticosteroid Secretion in the Dog

The present investigation was undertaken to know the effect of food ingestion on adrenal cortical secretion. In conscious dogs adrenal venous blood was collected before and after ingestion of food (boiled beef) and analyzed for 17-hydroxycorticosteroids (17-OHCS). The adrenal 17-OHCS secretion rate before the ingestion of food was 0.04-0.25μg/ kg/min. After the food ingestion it was increased only slightly and transitorily, the maximal secretion rate being 0.36-0.55μg/kg/min.