In Vitro and in Silico Assessment of the Potential of Niaouli Essential Oil as a Quorum Sensing Inhibitor of Biofilm Formation and its Effects on Fibroblast Cell Viability

In Vitro and in Silico Assessment of the Potential of Niaouli Essential Oil as a Quorum Sensing Inhibitor of Biofilm Formation and its Effects on Fibroblast Cell Viability

Abstract Essential oils (EO), as new bioactive compounds, have been used for pharmaceutical applications. In this study, EO of Niaouli was found to have a high content in 1,8-cineole (58.53%). Furthermore, pinene, α-terpineol, nerolidol and ledene were found to be its components with an abundance of...

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Veröffentlicht in:Brazilian Archives of Biology and Technology 2021-01, Vol.64
Hauptverfasser: Onem, Ebru, Soyocak, Ahu, Muhammed, Muhammed Tilahun, Ak, Ayse
Format: Artikel
Sprache:eng
Schlagworte:
Biofilm
fibroblast
molecular docking
niaouli
viability
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Zusammenfassung:Abstract Essential oils (EO), as new bioactive compounds, have been used for pharmaceutical applications. In this study, EO of Niaouli was found to have a high content in 1,8-cineole (58.53%). Furthermore, pinene, α-terpineol, nerolidol and ledene were found to be its components with an abundance of above 2%. Niaouli EO also had effects as inhibitor of Pseudomonas aeruginosa PAO1 biofilm formation (p
ISSN:1516-8913
1678-4324
DOI:10.1590/1678-4324-2021200782