Major oncological surgery reduces muscular function in patients with or without nutritional risk

ABSTRACT Objectives : to investigate the impact of oncological surgical procedures on the muscle function of patients with and without nutritional risk. Methods: cross-sectional study conducted with cancer patients undergoing major operations between July 2018 to March 2019 in Cuiabá, Mato Grosso, Brazil. Patients were assessed preoperatively for the nutritional risk by the Nutricional Risk Screening-2002, and handgrip strength (FPP) was assessed both on the pre- and 2nd and 5th postoperative days (PO). Results: 92 patients were evaluated, of whom 55.4% were men and 44.6% women, with a mean age (SD) of 64 (10.81) for patients at risk and 51 (12.99) for patients without nutritional risk. The preoperative nutritional risk evaluation indicated that 34.8% of the patients had no risk and 65.2% had a nutritional risk. The FPP was lower (p = 0.008) in the group with nutritional risk in the preoperative period. In both groups, there was a significant drop in FPP on the 2nd PO day. The preoperative FPP compared with the 2nd PO FPP was more pronounced in patients without nutritional risk (p = 0.039). Patients with nutritional risk had a longer hospital stay (p = 0.049). Conclusion: surgical trauma causes loss of muscle function in the early PO. Patients without nutritional risk have a more significant decrease in muscle strength after surgical oncological procedures than those with nutritional risk. These results may infer the need to implement pre-habilitation in all patients who will undergo major oncological procedures. RESUMO Objetivo: investigar o impacto de procedimentos cirúrgicos oncológicos na função muscular de pacientes com e sem risco nutricional. Métodos: estudo observacional realizado com pacientes oncológicos candidatos a operações de grande porte entre julho de 2018 a março de 2019 em Cuiabá, Mato Grosso, Brasil. Os pacientes foram avaliados no pré-operatório quanto ao risco nutricional pela Nutricional Risk Screening-2002 e avaliou-se a força de preensão palmar (FPP) tanto no pré- quanto no 2º e 5º dia de pós-operatório (PO). Resultados: Foram avaliados 92 pacientes, dos quais 55,4% eram homens e 44,6% mulheres, com média (DP) de idade de 64 (10,81) para pacientes com risco e 51 (12,99) para pacientes sem risco nutricional. A avaliação nutricional pré-operatória mostrou que 34,8% dos pacientes não tinham risco e 65,2% apresentavam risco nutricional. A FPP foi menor (p=0,008) no grupo com risco nutricional no pré-operatório. Em ambos os grupos houve