Structural and functional state of the skin microcirculation in men with different phenotypes of hypertension of low and moderate cardiovascular risk

Aim . To study the structural and functional state of skin microcirculation in working-age men with different phenotypes of hypertension (HTN) of low/moderate cardiovascular risk. Material and methods . A total of 218 healthy men underwent total blood count and biochemical blood tests, volumetric sphygmography, videocapillaroscopy, laser Doppler flowmetry at rest and with const­rictor and dilator tests, photoplethysmography, flow-mediated vasodilation of the brachial artery, cardiac and main artery ultrasound, 24-hour blood pressure (BP) monitoring. Based on the 24-hour BP monitoring, three following groups were formed: normal BP (NBP) group — 72 men, isolated diastolic hypertension (IDH) group — 70, systolic-diastolic hypertension (SDH) group — 76. Results . According to videocapillaroscopy and laser Doppler flow­metry, no reliable intergroup differences were found at the level of capillaries and precapillary arterioles. According to photoplethymography, men with SDH compared to the NBP group had higher AIp75 (augmentation index normalized to 75 bpm) (7,35 vs -5,4%; p