Iodide goiter in the newborn

A hyperthyroid mother, treated with potassium iodide, gave birth to a baby with an enormous goiter. The infant, although hypothyroid, had massive cardiomegaly and high output failure due to a shunt across the vessels of the goiter. Administration of thyroid caused shrinkage of the gland and concomit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pediatrics (Evanston) 1971-03, Vol.47 (3), p.510-515
Hauptverfasser: Senior, B, Chernoff, H L
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A hyperthyroid mother, treated with potassium iodide, gave birth to a baby with an enormous goiter. The infant, although hypothyroid, had massive cardiomegaly and high output failure due to a shunt across the vessels of the goiter. Administration of thyroid caused shrinkage of the gland and concomitantly the heart became smaller. The infant then developed hyperthyroidism which persisted for several months. The late stage of onset of hyperthyroidism in the infant, the inability to demonstrate LATS in mother or child, and the resemblance to other reported cases of iodide goiter in infancy together indicate that the hyperthyroidism may have been a consequence of the iodide goiter rather than a result of the transmission of LATS from the hyperthyroid mother.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.47.3.510