Dual Energy CT for determining the severity of acute pancreatitis

We aimed to quantitatively compare the iodine concentration measured by Dual Energy Computed Tomography （CT） between acute and mild pancreatitis cases and to evaluate the accuracy of the severity assessment of acute pancreatitis using Dual Energy CT. The contrast CT grade based on the guidelines in Japan and definitive diagnoses were evaluated. Iodine concentrations and C-reactive protein （CRP） levels were compared between mild and severe acute pancreatitis. The CECT grading diagnosed five false negative cases out of 41 patients. Only when the CRP reached the highest level, there was a significant difference between severe and mild cases. There were significant differences between the iodine concentration of severe and mild cases. Our results demonstrated measuring iodine concentration using Dual Energy CT is useful for severity assessment of acute pancreatitis.