NO donors with anticancer activity

NO donors with anticancer activity

Nitric oxide (NO) radicals, endogenously produced from L-arginine or supplied by NO-releasing donors, are involved in numerous physiological and pathological processes. Although there has been rapid growth in NO research, cancer research still remains in its infancy. A few reports suggest that NO ha...

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Veröffentlicht in:Expert opinion on therapeutic patents 2002-06, Vol.12 (6), p.819-826
Hauptverfasser: Janczuk, Adam J, Jia, Qiang, Xian, Ming, Wen, Zhong, Wang, Peng George, Cai, Tingwei
Format: Artikel
Sprache:eng
Schlagworte:
anticancer
antitumour
nitric oxide (NO)
nitric oxide donor
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Zusammenfassung:Nitric oxide (NO) radicals, endogenously produced from L-arginine or supplied by NO-releasing donors, are involved in numerous physiological and pathological processes. Although there has been rapid growth in NO research, cancer research still remains in its infancy. A few reports suggest that NO has some anticancer properties, yet others implicate NO in tumour promotion. This article will focus on the anticancer activity of NO donors that have been claimed in patents between 1998 and 2001.
ISSN:1354-3776
1744-7674
DOI:10.1517/13543776.12.6.819