New Withanolides from Fresh Berries of Withania somnifera

The chloroform extract of the fresh berries of Withania somnifera has been investigated to afford stigmasterol, its glucoside, withanone, 27-hydroxy withanolide A along with two new withanolides, namely, iso-withanone (1) and 6α,7α-epoxy-1α,3β ,5α-trihydroxy-witha-24-enolide (2). Compound 1 possesse...

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Veröffentlicht in:Zeitschrift für Naturforschung. B, A journal of chemical sciences A journal of chemical sciences, 2006-09, Vol.61 (9), p.1143-1147
Hauptverfasser: Lal, Payare, Misra, Laxminarain, Sangwan, Rajender S., Tuli, Rakesh
Format: Artikel
Sprache:eng
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Zusammenfassung:The chloroform extract of the fresh berries of Withania somnifera has been investigated to afford stigmasterol, its glucoside, withanone, 27-hydroxy withanolide A along with two new withanolides, namely, iso-withanone (1) and 6α,7α-epoxy-1α,3β ,5α-trihydroxy-witha-24-enolide (2). Compound 1 possesses an uncommon 17α-oriented side chain whereas compound 2 has 1α,3β - dihydroxy group which is a molecule of biogenetic significance for withasteroids.
ISSN:0932-0776
1865-7117
DOI:10.1515/znb-2006-0914