Zur Biosynthese der Peptidalkaloide von Claviceps purpurea / Biosynthesis of Peptide Alkaloids of Claviceps purpurea

Zur Biosynthese der Peptidalkaloide von Claviceps purpurea / Biosynthesis of Peptide Alkaloids of Claviceps purpurea

Using a strain of Claviceps purpurea which produces under submerged conditions chanoclavine, ergometrine and mainly ergotoxine the biosynthesis of ergoline derivatives has been studied. DL-Tryptophan- (ring-2- C) is specifically incorporated into the lysergic acid moiety of ergotoxine· alkaloids. L-...

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Veröffentlicht in:Zeitschrift für Naturforschung. B, A journal of chemical sciences A journal of chemical sciences, 1970-02, Vol.25 (2), p.196-199
Hauptverfasser: Gröger, D., Erge, D.
Format: Artikel
Sprache:eng
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Zusammenfassung:Using a strain of Claviceps purpurea which produces under submerged conditions chanoclavine, ergometrine and mainly ergotoxine the biosynthesis of ergoline derivatives has been studied. DL-Tryptophan- (ring-2- C) is specifically incorporated into the lysergic acid moiety of ergotoxine· alkaloids. L-Proline-U- C serves as a precursor of the proline-part of the peptid-chain of ergotoxine.
ISSN:0932-0776
1865-7117
DOI:10.1515/znb-1970-0216