Altered chemosensitivity to CO 2 during exercise

Altered chemosensitivity to CO 2 during exercise

The effect of exercise on chemosensitivity to carbon dioxide (CO ) has been controversial. Most studies have been based on rebreathing to alter inspired CO which is poorly tolerated in exercise. Instead, inhaling a fixed 3% CO from rest to moderate exercise was found to be well tolerated by seven no...

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Veröffentlicht in:Physiological reports 2021-06, Vol.9 (11), p.e14882
Hauptverfasser: Yamashiro, Stanley M, Kato, Takahide, Matsumoto, Takaaki
Format: Artikel
Sprache:eng
Schlagworte:
Carbon Dioxide - pharmacology
Chemoreceptor Cells - drug effects
Exercise - physiology
Humans
Hypercapnia - metabolism
Hypercapnia - physiopathology
Male
Respiration - drug effects
Young Adult
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Zusammenfassung:The effect of exercise on chemosensitivity to carbon dioxide (CO ) has been controversial. Most studies have been based on rebreathing to alter inspired CO which is poorly tolerated in exercise. Instead, inhaling a fixed 3% CO from rest to moderate exercise was found to be well tolerated by seven normal subjects enabling CO chemosensitivity to be studied with minimal negative reaction. Results showed that chemosensitivity to CO following 5-6 min of stimulation was significantly enhanced during mild exercise (p 
ISSN:2051-817X
DOI:10.14814/phy2.14882