The therapeutic effect of goreisan to oligohydramnios — Gorei-San increase the single deepest pocket in oligohydramnios

Aim: Oligohydramnios contributes to a negative fetal prognosis. Management of oligohydramnios in obstetric clinical practice is important. We assessed the clinical efficacy of Gorei-San for the treatment of oligohydramnios.Methods: Single deepest pocket (SDP) changes before and after treatment for oligohydramnios (SDP decrease to less than 3 cm) were examined. A total of 51 pregnant mothers who were experiencing oligohydramnios were enrolled in the study. The changes in SDP were compared between 27 women treated with Gorei-San (7.5 g/day) and 24 untreated women. The first measurements of SDP in both groups were obtained when the SDP had decreased to less than 3 cm (start point: SP), and the second measurements were obtained at the next regular examination (end point: EP).Results: The average SDP significantly increased in women treated with Gorei-San from the SP (2.37±0.41 cm) (mean±SD) to the EP (3.15±0.62 cm) (mean±SD) (P