Organization and functioning of the neuroendocrine system

Recent progress in neuroendocrinology provided a basis for the formulation of the integral strategy for the systemic treatment of endocrine diseases. This review presents experimental and clinical evidence of the presence in the hypothalamus of specific receptors of hormones produced by the peripheral endocrine glands and trophic pituitary hormones. Synthesis of specific hypothalamic substances (releasing hormones) maintains the interplay between the neural and endocrine structures. The positive and negative feedback mechanisms in the body ensure the stable functioning of all its organs and systems.