Azathioprine-Associated Pulmonary Dysfunction

We present a case of azathioprine-associated alveolitis diagnosed by gallium-67 scanning and transbronchial biopsy. The patient denied respiratory symptoms, exhibited spiking fevers, and had normal chest roentgenograms. Allopurinol inhibition of azathioprine metabolism may have been a contributing f...

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Veröffentlicht in:	Chest 1983-04, Vol.83 (4), p.696-698
Hauptverfasser:	Krowka, Michael J., Breuer, Richard I., Kehoe, Thomas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allopurinol - pharmacology Allopurinol - therapeutic use Azathioprine - adverse effects Azathioprine - antagonists & inhibitors Crohn Disease - drug therapy Humans Inflammation - chemically induced Kidney Calculi - prevention & control Lung Diseases - chemically induced Male Pulmonary Alveoli - drug effects
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Zusammenfassung:	We present a case of azathioprine-associated alveolitis diagnosed by gallium-67 scanning and transbronchial biopsy. The patient denied respiratory symptoms, exhibited spiking fevers, and had normal chest roentgenograms. Allopurinol inhibition of azathioprine metabolism may have been a contributing factor.
ISSN:	0012-3692 1931-3543
DOI:	10.1378/chest.83.4.696