Spatial polarimetric second harmonic generation evaluation of collagen in a hypophosphatasia mouse model

Polarization-resolved second harmonic generation (pSHG) is a label-free method that has been used in a range of tissue types to describe collagen orientation. In this work, we develop pSHG analysis techniques for investigating cranial bone collagen assembly defects occurring in a mouse model of hypo...

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Veröffentlicht in:Biomedical optics express 2024-12, Vol.15 (12), p.6940
Hauptverfasser: Zheng, Tianyi, Pendleton, Emily G., Barrow, Ruth P., Maslesa, Ana D., Kner, Peter A., Mortensen, Luke J.
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Sprache:eng
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