Skin Breakdown and Blisters from Senna-Containing Laxatives in Young Children

BACKGROUND: At the direction of the Food and Drug Administration, phenolphthalein was removed from all over-the-counter laxatives in 1999. Phenolphthalein was then replaced in most laxative products with the natural product senna from Cassia acutifolia Delile, which contains various anthraquinones....

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Veröffentlicht in:The Annals of pharmacotherapy 2003-05, Vol.37 (5), p.636-639
Hauptverfasser: Spiller, Henry A, Winter, Mark L, Weber, Julie A, Krenzelok, Edward P, Anderson, Deborah L, Ryan, Mark L
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Sprache:eng
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Zusammenfassung:BACKGROUND: At the direction of the Food and Drug Administration, phenolphthalein was removed from all over-the-counter laxatives in 1999. Phenolphthalein was then replaced in most laxative products with the natural product senna from Cassia acutifolia Delile, which contains various anthraquinones. No data are available on the safety of senna use in children
ISSN:1060-0280
1542-6270
DOI:10.1345/aph.1C439