Can Platelet Mass Index Be Used as a Prognostic Marker in Children Diagnosed with Multisystem Inflammatory Syndrome Associated with Coronavirus?

Objective: We’ve aimed at evaluating whether the platelet mass index (PMI) can be a prognostic marker for children diagnosed with MIS-C. Material and Methods: 31 children diagnosed with MIS-C and treated at our university hospital between March 2020 and November 2021 were included. Demographic data,...

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Veröffentlicht in:Turkish Journal of Pediatric Disease 2023-03, p.1-6
Hauptverfasser: EKER, İbrahim, BÜKÜLMEZ, Ayşegül, PEKTAS, Ayhan, DÜZENLİ KAR, Yeter, EROĞLU, Nilgün, ÇELEGEN, Mehmet, ŞENOL, Yiğit, ÇITAK, Ayşe, GÜL, Baran, SOYALAN, Begüm, DURMUŞ, Deniz, KARATAŞ, Melissa
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Sprache:tur
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Zusammenfassung:Objective: We’ve aimed at evaluating whether the platelet mass index (PMI) can be a prognostic marker for children diagnosed with MIS-C. Material and Methods: 31 children diagnosed with MIS-C and treated at our university hospital between March 2020 and November 2021 were included. Demographic data, clinical findings and laboratory values at the time of hospitalization, admission to the intensive care unit and duration of hospitalization were evaluated retrospectively. PMI of each patient at the time of hospitalization was calculated and recorded. Results: There was a statistically significant negative correlation between PMI and ferritin (r= -0.635, moderate, p400 ng/ml (1415.2; 533.4 – 3600.5) were statistically lower compared to the median PMI values of the patients whose ferritin level was ≤400 ng/ml (2705.7; 1395.2 – 9167.6).Conclusion: The findings in our study demonstrate that low PMI levels identified in children with MIS-C at the time of diagnosis may be with more severe clinical courses Amaç: Trombosit kitle indeksinin (TKİ) MIS-C tanısı alan çocuklarda prognostik bir belirteç olup olmadığının değerlendirilmesi. Gereç ve Yöntemler: Mart 2020 ile Kasım 2021 tarihleri arasında üniversite hastanemizde MIS-C tanısı konan ve tedavi gören 31 çocuk çalışmaya dahil edildi. Hastaneye yatış anındaki, yoğun bakıma yatış anındaki ve hastanedeki yatış süresince demografik veriler, klinik bulgular ve laboratuvar değerleri retrospektif olarak değerlendirildi. Her hastanın yatış anındaki TKİ değerleri hesaplandı ve kaydedildi. Bulgular: TKİ ile ferritin (r= -0.635, orta, p
ISSN:1307-4490
DOI:10.12956/tchd.1180080