Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck
A prospective study was carried out to investigate the effectiveness and feasibility of two courses of combination therapy with COB every three weeks prior to surgery and/or radiotherapy in 70 patients with advanced untreated epidermoid cancer of the head and neck. Of 65 patients evaluable after two...
Gespeichert in:
| Veröffentlicht in: | The Laryngoscope 1980-08, Vol.90 (8), p.1273-1280 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1280 |
|---|---|
| container_issue | 8 |
| container_start_page | 1273 |
| container_title | The Laryngoscope |
| container_volume | 90 |
| creator | Peppard, Sean B. Al-Sarraf, Muhyi Powers, William E. Loh, John K. Weaver, Arthur W. |
| description | A prospective study was carried out to investigate the effectiveness and feasibility of two courses of combination therapy with COB every three weeks prior to surgery and/or radiotherapy in 70 patients with advanced untreated epidermoid cancer of the head and neck. Of 65 patients evaluable after two courses of chemotherapy, 16 had a complete remission (CR) and 36 had a partial remission (PR; > 50% — < 100%) for a total major response rate of 80%. |
| doi_str_mv | 10.1288/00005537-198008000-00003 |
| format | Article |
| fullrecord | <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1288_00005537_198008000_00003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_WNG_HLZMKXNM_T</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4093-6c3d3d9b6f42b6e8ede731f7376c6af5bef90bb4b880b4dee77d6a4358a5e8763</originalsourceid><addsrcrecordid>eNqNUF1v1DAQtBBVOQo_AcmPINXUPsex81gd0KJei4SKKLxY_thQ04sdOblCfgt_FqdX7hnLktezOzPaQQgz-pYtlTqh5QjBJWGNorRcSmaIP0ELJjgjVdOIp2hB6ZITJZY3z9DzYfhJKZNc0EN0WDMhaS0X6M8qdTZEM4YUcWqxCwPpN-Ubt90xTtGl-xCPsYke2w2kbnIh4tcu2Te4zyFlPCY8bPMPyNM8dFKQbHxI4y1k00-4TBt_b6IDj7dxzGDGUkEfPOQuBY_d3MuzdaHgWzD-wSyCu3uBDlqzGeDl43uEvnx4f706J-tPZx9Xp2viKtpwUjvuuW9s3VZLW4MCD5KzVnJZu9q0wkLbUGsrqxS1lQeQ0tem4kIZAUrW_Aipna7LaRgytLqs1pk8aUb1HLf-F7fex_0A8UJ9taP2W9uB3xMf8y39d7v-r7CB6b919fr08zchynozOtuQnUwYRvi9lzH5ThcTKfTXqzN9vv5-eXFzdamv-V-aG6Ap</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Peppard, Sean B. ; Al-Sarraf, Muhyi ; Powers, William E. ; Loh, John K. ; Weaver, Arthur W.</creator><creatorcontrib>Peppard, Sean B. ; Al-Sarraf, Muhyi ; Powers, William E. ; Loh, John K. ; Weaver, Arthur W.</creatorcontrib><description>A prospective study was carried out to investigate the effectiveness and feasibility of two courses of combination therapy with COB every three weeks prior to surgery and/or radiotherapy in 70 patients with advanced untreated epidermoid cancer of the head and neck. Of 65 patients evaluable after two courses of chemotherapy, 16 had a complete remission (CR) and 36 had a partial remission (PR; > 50% — < 100%) for a total major response rate of 80%.</description><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 1531-4995</identifier><identifier>DOI: 10.1288/00005537-198008000-00003</identifier><identifier>PMID: 6157067</identifier><language>eng</language><publisher>Hoboken, NJ: John Wiley & Sons, Inc</publisher><subject>Bleomycin - therapeutic use ; Carcinoma, Squamous Cell - drug therapy ; Cisplatin - therapeutic use ; Drug Therapy, Combination ; Evaluation Studies as Topic ; Female ; Head and Neck Neoplasms - drug therapy ; Humans ; Male ; Middle Aged ; Vincristine - therapeutic use</subject><ispartof>The Laryngoscope, 1980-08, Vol.90 (8), p.1273-1280</ispartof><rights>Copyright © 1980 The Triological Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4093-6c3d3d9b6f42b6e8ede731f7376c6af5bef90bb4b880b4dee77d6a4358a5e8763</citedby><cites>FETCH-LOGICAL-c4093-6c3d3d9b6f42b6e8ede731f7376c6af5bef90bb4b880b4dee77d6a4358a5e8763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6157067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Peppard, Sean B.</creatorcontrib><creatorcontrib>Al-Sarraf, Muhyi</creatorcontrib><creatorcontrib>Powers, William E.</creatorcontrib><creatorcontrib>Loh, John K.</creatorcontrib><creatorcontrib>Weaver, Arthur W.</creatorcontrib><title>Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck</title><title>The Laryngoscope</title><addtitle>The Laryngoscope</addtitle><description>A prospective study was carried out to investigate the effectiveness and feasibility of two courses of combination therapy with COB every three weeks prior to surgery and/or radiotherapy in 70 patients with advanced untreated epidermoid cancer of the head and neck. Of 65 patients evaluable after two courses of chemotherapy, 16 had a complete remission (CR) and 36 had a partial remission (PR; > 50% — < 100%) for a total major response rate of 80%.</description><subject>Bleomycin - therapeutic use</subject><subject>Carcinoma, Squamous Cell - drug therapy</subject><subject>Cisplatin - therapeutic use</subject><subject>Drug Therapy, Combination</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Head and Neck Neoplasms - drug therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Vincristine - therapeutic use</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUF1v1DAQtBBVOQo_AcmPINXUPsex81gd0KJei4SKKLxY_thQ04sdOblCfgt_FqdX7hnLktezOzPaQQgz-pYtlTqh5QjBJWGNorRcSmaIP0ELJjgjVdOIp2hB6ZITJZY3z9DzYfhJKZNc0EN0WDMhaS0X6M8qdTZEM4YUcWqxCwPpN-Ubt90xTtGl-xCPsYke2w2kbnIh4tcu2Te4zyFlPCY8bPMPyNM8dFKQbHxI4y1k00-4TBt_b6IDj7dxzGDGUkEfPOQuBY_d3MuzdaHgWzD-wSyCu3uBDlqzGeDl43uEvnx4f706J-tPZx9Xp2viKtpwUjvuuW9s3VZLW4MCD5KzVnJZu9q0wkLbUGsrqxS1lQeQ0tem4kIZAUrW_Aipna7LaRgytLqs1pk8aUb1HLf-F7fex_0A8UJ9taP2W9uB3xMf8y39d7v-r7CB6b919fr08zchynozOtuQnUwYRvi9lzH5ThcTKfTXqzN9vv5-eXFzdamv-V-aG6Ap</recordid><startdate>198008</startdate><enddate>198008</enddate><creator>Peppard, Sean B.</creator><creator>Al-Sarraf, Muhyi</creator><creator>Powers, William E.</creator><creator>Loh, John K.</creator><creator>Weaver, Arthur W.</creator><general>John Wiley & Sons, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198008</creationdate><title>Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck</title><author>Peppard, Sean B. ; Al-Sarraf, Muhyi ; Powers, William E. ; Loh, John K. ; Weaver, Arthur W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4093-6c3d3d9b6f42b6e8ede731f7376c6af5bef90bb4b880b4dee77d6a4358a5e8763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Bleomycin - therapeutic use</topic><topic>Carcinoma, Squamous Cell - drug therapy</topic><topic>Cisplatin - therapeutic use</topic><topic>Drug Therapy, Combination</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Head and Neck Neoplasms - drug therapy</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Vincristine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peppard, Sean B.</creatorcontrib><creatorcontrib>Al-Sarraf, Muhyi</creatorcontrib><creatorcontrib>Powers, William E.</creatorcontrib><creatorcontrib>Loh, John K.</creatorcontrib><creatorcontrib>Weaver, Arthur W.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>The Laryngoscope</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peppard, Sean B.</au><au>Al-Sarraf, Muhyi</au><au>Powers, William E.</au><au>Loh, John K.</au><au>Weaver, Arthur W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck</atitle><jtitle>The Laryngoscope</jtitle><addtitle>The Laryngoscope</addtitle><date>1980-08</date><risdate>1980</risdate><volume>90</volume><issue>8</issue><spage>1273</spage><epage>1280</epage><pages>1273-1280</pages><issn>0023-852X</issn><eissn>1531-4995</eissn><abstract>A prospective study was carried out to investigate the effectiveness and feasibility of two courses of combination therapy with COB every three weeks prior to surgery and/or radiotherapy in 70 patients with advanced untreated epidermoid cancer of the head and neck. Of 65 patients evaluable after two courses of chemotherapy, 16 had a complete remission (CR) and 36 had a partial remission (PR; > 50% — < 100%) for a total major response rate of 80%.</abstract><cop>Hoboken, NJ</cop><pub>John Wiley & Sons, Inc</pub><pmid>6157067</pmid><doi>10.1288/00005537-198008000-00003</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0023-852X |
| ispartof | The Laryngoscope, 1980-08, Vol.90 (8), p.1273-1280 |
| issn | 0023-852X 1531-4995 |
| language | eng |
| recordid | cdi_crossref_primary_10_1288_00005537_198008000_00003 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Bleomycin - therapeutic use Carcinoma, Squamous Cell - drug therapy Cisplatin - therapeutic use Drug Therapy, Combination Evaluation Studies as Topic Female Head and Neck Neoplasms - drug therapy Humans Male Middle Aged Vincristine - therapeutic use |
| title | Combination of cis-platinum, oncovin, and bleomycin (cob) prior to surgery and/or radiotherapy in advanced untreated epidermoid cancer of the head and neck |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T23%3A24%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Combination%20of%20cis-platinum,%20oncovin,%20and%20bleomycin%20(cob)%20prior%20to%20surgery%20and/or%20radiotherapy%20in%20advanced%20untreated%20epidermoid%20cancer%20of%20the%20head%20and%20neck&rft.jtitle=The%20Laryngoscope&rft.au=Peppard,%20Sean%20B.&rft.date=1980-08&rft.volume=90&rft.issue=8&rft.spage=1273&rft.epage=1280&rft.pages=1273-1280&rft.issn=0023-852X&rft.eissn=1531-4995&rft_id=info:doi/10.1288/00005537-198008000-00003&rft_dat=%3Cistex_cross%3Eark_67375_WNG_HLZMKXNM_T%3C/istex_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/6157067&rfr_iscdi=true |