Case Report: A rare case of renal-type clear cell carcinoma of the prostate [version 1; peer review: 1 approved with reservations]

Renal-type clear cell carcinoma (RTCCC) of the prostate is a rare form of kidney cancer that is infrequently reported in the literature. Here we describe the case of an 81-year-old male patient with a hard, immovable mass on his enlarged prostate, which was discovered through a digital rectal examination. His prostate-specific antigen (PSA) level was 23.01 ng/ml, and bone multi-slice computed tomography scans revealed several osteoblastic lesions on the inferior ramus of his bilateral pubic bone. Tissue recovered during the trans urethral resection of the prostate was indicative of RTCCC with typical prostatic adenocarcinoma (Gleason score 3 + 4 = 7). Concerning treatment course, bilateral subcapsular orchiectomy was chosen over medical hormonal therapy. Upon follow-up 12 months post-surgery, his lower urinary tract symptoms were nearly resolved and his serum PSA level had decreased to 3.2 ng/ml. Accurate RTCCC diagnosis remains a pressing concern that warrants further investigation to optimize treatment selection and patient outcome.