Effect of Cefazolin on endometrial cytology and reagent test strips parameters in bovine endometritis

Endometritis is one of uterine disorders in dairy cows causing low fertility. This study explored effects of intrauterine (IU) infusion of Cefazolin on endometrial cytology and reagent test strips parameters (leukocyte esterase [LE] and pH) in bovine subclinical endometritis. A total of 90 cows at 49-56 days in milk (DIM) diagnosed for subclinical endometritis were divided randomlyinto three groups, group I (n = 35), treated with IU infusion of 2 grams Cefazolin (Zinol ®, Pharco) diluted with 50 ml saline; group II (n = 28), treated with IU infusion of 2 gramsCephalexin (Ceporex®, GlaxoSmithKline) diluted with 50 ml saline; group III (n = 27), cows kept as untreated control. Cytological examination and reagent test strips were performed in uterine material derived with the cotton swab technique before treatment program and repeated two times later, in 10 days interval. The cows were artificially inseminated at first oestrous after the end of treatment program and conception rates were evaluated. After the end of treatment program, polymorphonuclear cells (PMN) decreased significantly (P