Bredinin-induced chromosome aberrations in L5178Y cells
Bredinin, an effective inhibitor of nucleic acid synthesis, induced chromosome aberrations during the S and G2 phases of the mitotic cycle in L5178Y mouse leukemia cells. The maximum sensitivity to bredinin was during the latter half of S. The chromosome aberrations were prevented by simultaneous ad...
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| Veröffentlicht in: | Idengaku zasshi 1976, Vol.51(1), pp.61-64 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng ; jpn |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Bredinin, an effective inhibitor of nucleic acid synthesis, induced chromosome aberrations during the S and G2 phases of the mitotic cycle in L5178Y mouse leukemia cells. The maximum sensitivity to bredinin was during the latter half of S. The chromosome aberrations were prevented by simultaneous addition of guanylic acid and bredinin. |
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| ISSN: | 0021-504X 1880-5787 |
| DOI: | 10.1266/jjg.51.61 |