Micro-Synthesis and Electron Ionization Mass Spectral Analysis of O-Alkyl N,N-Dialkylphosphoramidocyanidates

This communication describes the microsynthesis and gas chromatographic/mass spectrometric (GC/MS) analysis of O-alkyl N,N-dialkylphosphoramidocyanidates (ADAPCs), which are analogs of the chemical warfare agent, Tabun. The study was undertaken with a view to develop a spectral database of ADAPCs for verification purposes of the Chemical Weapons Convention (CWC). Reported microsynthetic approaches have advantages over traditional synthesis in terms of efficiency, synthetic waste and exposure to toxic chemicals. GC/MS analysis of a variety of these compounds (ADAPCs) was performed. Based on the obtained mass spectra of structurally diverse ADAPCs, the fragmentation routes are proposed, which explains most of the characteristic ions.