Time Course of Platelet Activation and von Willebrand Factor in Patients With Non-Valvular Atrial Fibrillation After Ischemic Stroke: Evaluation of Prognostic Determinants

Time Course of Platelet Activation and von Willebrand Factor in Patients With Non-Valvular Atrial Fibrillation After Ischemic Stroke: Evaluation of Prognostic Determinants

Background The present study investigated serial changes in platelet activation (expressed by CD62p) and von Willebrand factor (VWF), and the correlation between increased CD62p expression, VWF and brain infarct volume (BIV: measured by magnetic resonance imaging), and prognostic determinants in non...

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Veröffentlicht in:Circulation Journal 2007, Vol.71(3), pp.321-326
Hauptverfasser: Yip, Hon-Kan, Lai, Shung-Lon, Lan, Min-Yu, Chang, Wen-Neng, Liu, Josef S., Kao, Yi-Fen, Chang, Yung-Yee, Lu, Cheng-Hsien, Chen, Wei-Hsi, Lin, Hung-Hseng, Liou, Chia-Wei
Format: Artikel
Sprache:eng
Schlagworte:
Brain infarct volume
Ischemic stroke
Non-valvular atrial fibrillation
Platelet activation
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Zusammenfassung:Background The present study investigated serial changes in platelet activation (expressed by CD62p) and von Willebrand factor (VWF), and the correlation between increased CD62p expression, VWF and brain infarct volume (BIV: measured by magnetic resonance imaging), and prognostic determinants in non-valvular atrial fibrillation (NVAF) patients after acute ischemic stroke (IS). Methods and Results CD62p expression and plasma VWF concentrations were serially measured (
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.71.321