Syntheses of 1-Acyl-3-phenylacetylurea Derivatives
In order to reduce the side effect of N-phenylacetylureas, hitherto used as anticonvulsants, 1-acyl-3-phenylacetylureas were prepared by acylation of N-phenylacetylureas or by the reaction of acylisocyanates and acylamides. Of the compounds synthesized, 1-acetyl-3-(1-ethylphenylacetyl)urea was found...
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| Veröffentlicht in: | YAKUGAKU ZASSHI 1963/08/25, Vol.83(8), pp.753-756 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng ; jpn |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | In order to reduce the side effect of N-phenylacetylureas, hitherto used as anticonvulsants, 1-acyl-3-phenylacetylureas were prepared by acylation of N-phenylacetylureas or by the reaction of acylisocyanates and acylamides. Of the compounds synthesized, 1-acetyl-3-(1-ethylphenylacetyl)urea was found to be a convulsant with small side effect. |
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| ISSN: | 0031-6903 1347-5231 |
| DOI: | 10.1248/yakushi1947.83.8_753 |