Increase of Kidney Calcium and Decrease of Serum Glucose in Rats caused by the Drinking of Water containing Inorganic Tin

The effect of tin on body weight, serum glucose level, and calcium concentration in renal cortex was studied in rats that had ingested water containing 50 ppm tin for 100 days. The body weight and the wet weight of kidneys were significantly decreased by drinking of water containing tin compared with those of control rats. There was also a significant reduction of serum glucose and a significant increase in renal cortex after drinking of water containing tin. The present study suggests that the toxicity of tin cannot be neglected.