A SHORT STEP AND PRACTICAL SYNTHESIS OF MYO-INOSITOL 1, 3, 4, 5-TETRAKISPHOSPHATE

The reaction of myo-inositol with benzoly chloride gave 1, 3, 4, 5-tetra-O-benzoyl-myo-inositol as a major product which was conveniently converted to myo-inositol 1, 3, 4, 5-tetrakisphosphate. The tetrabenzoate was optically resolved by means of chiral column chromatography using Chiralcel OD.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 1990/02/25, Vol.38(2), pp.562-563
Hauptverfasser:	WATANABE, Yutaka, SHINOHARA, Tomoiti, FUJIMOTO, Takahiro, OZAKI, Shoichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	benzoylation Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry chiral column chromatography Exact sciences and technology myo-inositol myo-inositol 1, 3, 4, 5-tetrakisphosphate Organic chemistry phosphorylation Preparations and properties
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Beschreibung
Zusammenfassung:	The reaction of myo-inositol with benzoly chloride gave 1, 3, 4, 5-tetra-O-benzoyl-myo-inositol as a major product which was conveniently converted to myo-inositol 1, 3, 4, 5-tetrakisphosphate. The tetrabenzoate was optically resolved by means of chiral column chromatography using Chiralcel OD.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.38.562