SYNTHESIS OF (-)-ARISTEROMYCIN FROM D-GLUCOSE

(-)-Aristeromycin, a carbocyclic nucleoside with various biological activities, was synthesized from D-glucose using a Michael-type addition reaction of N6-benzoyladenine with a nitro-cyclopentene derivative as its key step.

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1989/09/25, Vol.37(9), pp.2555-2557
Hauptverfasser: YOSHIKAWA, Masayuki, OKAICHI, Yoshihiko, CHA, Bae Cheon, KITAGAWA, Isao
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Sprache:eng
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Zusammenfassung:(-)-Aristeromycin, a carbocyclic nucleoside with various biological activities, was synthesized from D-glucose using a Michael-type addition reaction of N6-benzoyladenine with a nitro-cyclopentene derivative as its key step.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.37.2555