Synthetic Studies on Acorane-Alaskane Sesquiterpenes. I. Total Synthesis of (±)-β-Acorenol

(±)-β-Acorenol (2) was synthesized by the metal-ammonia reduction of (1R*, 3aR*, 5aR*, 9aR*)-2, 3, 3a, 4-tetrahydro-1, 4, 4, 7-tetramethyl-1H, 5aH-cyclopenta [c] benzofuran (11a), which was prepared from the spirodienone 9a or 10a by reaction with methyllithium and subsequent Lewis acid treatment.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 1985/05/25, Vol.33(5), pp.1961-1968
Hauptverfasser:	IWATA, CHUZO, NAKAMURA, SHIZUO, SHINOO, YASUTAKA, FUSAKA, TAKAFUMI, OKADA, HIDEKO, KISHIMOTO, MICHIE, UETSUJI, HIDEKAZU, MAEZAKI, NAOYOSHI, YAMADA, MINORU, TANAKA, TETSUAKI
Format:	Artikel
Sprache:	eng
Schlagworte:	Alicyclic compounds, terpenoids, prostaglandins, steroids Chemistry conjugated diene 1, 4-reduction Exact sciences and technology Organic chemistry Preparations and properties Terpenoids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	(±)-β-Acorenol (2) was synthesized by the metal-ammonia reduction of (1R, 3aR, 5aR, 9aR)-2, 3, 3a, 4-tetrahydro-1, 4, 4, 7-tetramethyl-1H, 5aH-cyclopenta [c] benzofuran (11a), which was prepared from the spirodienone 9a or 10a by reaction with methyllithium and subsequent Lewis acid treatment.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.33.1961