A Convenient Synthesis of α-Substituted Cyclic α-Imino Acids

A Convenient Synthesis of α-Substituted Cyclic α-Imino Acids

Various α-substituted α-imino acids (6) were synthesized in good yields by the reaction of methyl α-substituted α-isocyanoacetates with alkylene bromides in the presence of sodium hydride, followed by cyclization and hydrolysis.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & pharmaceutical bulletin 1979/08/25, Vol.27(8), pp.1931-1934
Hauptverfasser: YASUO, HARUNORI, SUZUKI, MAMORU, YONEDA, NAOTO
Format: Artikel
Sprache:eng
Schlagworte:
ring transformation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Various α-substituted α-imino acids (6) were synthesized in good yields by the reaction of methyl α-substituted α-isocyanoacetates with alkylene bromides in the presence of sodium hydride, followed by cyclization and hydrolysis.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.27.1931