Preparation of Ester-group Substituted Allylic Zinc by Palladium-catalyzed Umpolung of γ-Acyloxy-α,β-unsaturated Ester by Bis(iodozincio)methane

Preparation of Ester-group Substituted Allylic Zinc by Palladium-catalyzed Umpolung of γ-Acyloxy-α,β-unsaturated Ester by Bis(iodozincio)methane

Treatment of γ-acyloxy-α,β-unsaturated ester with bis(iodozincio)methane in the presence of palladium catalyst gave an allylic zinc carrying an ester group; the allylic zinc, which is prepared by this umpolung process, reacts with ketones regioselectively.

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Veröffentlicht in:Chemistry letters 2010-02, Vol.39 (2), p.96-97
Hauptverfasser: Ueno, Shizue, Sada, Mutsumi, Matsubara, Seijiro
Format: Artikel
Sprache:eng
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Zusammenfassung:Treatment of γ-acyloxy-α,β-unsaturated ester with bis(iodozincio)methane in the presence of palladium catalyst gave an allylic zinc carrying an ester group; the allylic zinc, which is prepared by this umpolung process, reacts with ketones regioselectively.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2010.96